The Biological Sciences and Bioengineering Program at Sabancı University has ten faculty members who conduct research on modern biological problems. We offer a curriculum designed to encompass three areas of biological sciences: plant biology, bioinformatics and molecular and cellular biology. Our laboratories have modern infrastructure and cutting-edge research equipment. We are engaged in research and development projects and collaborate with researchers around the world.
Molecular and Cellular Biology
Mammals, including humans, are equipped with various defense mechanisms both at the organismal and cellular levels. Cells defend themselves against stressful conditions by activating various intracellular molecular responses. We study immune defense mechanisms, adaptive responses to oxidative stress in eukaryotic systems and cell death signaling in plant and mammalian cells. Stress induced signaling and eukaryotic gene expression is another focus of the research in this area.
Plant Molecular Biology and Genetics
Research in plant molecular biology and genetics is attracting increasing attention within the scientific community, because biotechnology research is extensively involved in product development for many agricultural, chemical, and pharmaceutical companies.
Plant Nutrition and Physiology
The group in Sabanci University is mainly investigating micronutrient deficiencies and heavy metal toxicities in crop plants. Special attention is being paid to biofortification of wheat with micronutrients, especially zinc, selenium and iron.
Structural and Computational Biology
The researchers are interested in structure-function relations of plants metallothioneins, structural analysis of plants TOLL-interleukin I like resistance genes. Functional analysis of plant G-proteins involved in signal transduction are achieved using modeling and synchrotron X-ray diffraction and scattering methods.
The researchers are mainly dealing with applications of data mining and machine learning techniques to several problems in Bioinformatics. These applications vary from identification of secondary structures in proteins to fold classification problem, from motif determination to biomedical text mining.