ME Seminar

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Robot-on-a-Chip

The recent advances in microfluidics and lab-on-chip systems have shown a great potential in biomedical applications. Microfluidic-based technology offers a convenient platform for cellular analyses of biological systems, as the small scale of micro-channels and devices allows producing scalable system architecture. Their inexpensive composition makes them a potential candidate for large scale production. Microfluidic technology covers not only the material phenomena but also the technology for manipulating and controlling the components as micro size particles in micro size artificial capillaries. Therefore, the integration of these technologies with micro robotic applications could be useful in the automation of cell manipulation for important areas such as single cell analysis, manipulation and treatment, including nuclear transplantation.

Robot-on-a-chip is also defined as Robochip, a microfluidic chip (Lab-on-a-chip) in which micro/nano robots are installed, and which is targeting the single-cell based measurement, analysis, cloning and anatomical manipulation to contribute to on-chip micromanipulation such as cell sorting. This research is targeting to create new field of study systematically from the basic to the applied field which is focusing on the field of microrobotics by mixing the field of robotics and micro/nano technology.

The development of microactuation mechanics in a microfluidic chip as a replacement for conventional cell manipulation has generated great interest recently. However, many preliminary sample preparation processes such as pipetting, mixing, sample selection, and centrifugation are carried out outside the chip without using microactuation mechanics. Therefore, it is crucial to handle cells gently and precisely by microactuation mechanics during scientific research and clinical diagnostic applications.

Short Bio 

Dr. Uvet holds a Bachelor of Science degree in Computer Engineering from Istanbul Kultur University which he acquired in 2004. Upon completing his undergraduate studies he started his master’s degree at Osaka University, Japan in System Innovation. Following his master’s studies on “Compact Vision System Design for Single Cell Analysis and Manipulation” at the Robotic Technologies Lab, he started his doctorate on “Micro/Nano Robotics” at the very same Robotic Technologies Lab of Osaka University, Japan.  In 2010, he continued his researches in Nagoya University, Micro-Nano System Engineering Department as a post-doctoral fellow. During this period, he worked on micro-robotic micromanipulation, microassembly, MEMS (sensors and actuators), mechanical manipulation of biological cells and tissue. Since 2011 October, He is currently full time Assistant Professor in Yildiz Technical University Mechatronics Department in Istanbul, Turkey.