Computational modelling for better tissue engineering
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  • Computational modelling for better tissue engineering

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Computational modelling for better tissue engineering

Prof. Hans Van Oosterwyck

Mechanical Engineering Department, KU Leuven University, Belgium

Tissue engineering aims at the restoration and improvement of damaged tissues and organs, by applying principles from engineering and life sciences. Dealing with (the creation of) living systems implies tremendous challenges in handling system complexity, meaning among others that system quantification and prediction is far from straightforward. In my talk I will present some examples on how computational modelling can help us in better quantifying and understanding tissue engineering systems for skeletal tissue regeneration (see also and


Hans Van Oosterwyck (DOB 02.02.1972) holds an MSc degree in Materials Engineering (1995) and a PhD degree in Engineering (2000), both obtained at KU Leuven (Leuven, Belgium). He has been a postdoctoral fellow at the AO Research Institute (Davos, Switzerland) in 2004-2005 and a visiting scientist at the University of Zaragoza (Spain) in 2009.

He currently is a professor at and chair of the Biomechanics section (Mechanical Engineering Department) at KU Leuven, where he is heading the Mechanobiology and Tissue Engineering research group, and a visiting professor at Ghent University (Ghent, Belgium). He is a member of Prometheus, the Leuven R&D Division for Skeletal Tissue Engineering. In 2012 he was awarded an ERC Starting Grant on the role of cell-matrix interaction in angiogenesis (‘MAtrix: In silico and in vitro Models of Angiogenesis: unraveling the role of the extracellular matrix’). His research focuses on the development of quantitative tools for unraveling the role of the microenvironment for cell fate, in particular the development of multiscale computational models for studying the importance of mechanics and mass transport for angiogenesis and bone regeneration. His research group is strongly interdisciplinary and combines computational modelling with experimental techniques, adopted from various fields, such as cell and tissue mechanics, cell biology, biomaterials and biophysics.

Hans Van Oosterwyck has been a Council Member of the European Society of Biomechanics (ESB) since 2006. He has been the President of the ESB between 2012-2014.