Faculty of Engineering and Natural Sciences
Hierarchical Structures through Molecular Recognition and Self-Assembly & Biological Applications of Phase Separated Gold Nanoparticles
Dr. Oktay Uzun,
Massachusetts Institute of Technology, Materials Science and Engineering
Hierarchy and complexity are typical features of many self-assembled biological structures and are emerging as an important characteristic in the development of supramolecular materials. The scientific and technological impact of any new class of mesoscale material depends on the ability to control the size, morphology and aggregate structure of their nanoscale components. Nanoparticles, with their unique size dependent electronic, magnetic and optical properties, can be used as the primary building block for the construction of supramolecular materials. As a secondary component, synthetic polymers utilizing noncovalent interactions can be used for the design and construction of materials with tunable properties. In order to achieve this goal, we have used a reversible polymer side chain modification method and showed that this approach can be used to control the size of nanoparticle aggregates, interparticle spacing between nanoparticles, surface properties and polymer aggregate microstructure.
Second part of the talk will focus on a simple method to place target molecules specifically at two diametrically opposed positions in the molecular coating of metal nanoparticles. The approach is based on the functionalization of the polar singularities that must form when a curved surface is coated with ordered monolayers, such as a phase-separated mixture of ligands. The molecules placed at these polar defects have been used as chemical handles to form nanoparticle chains that in turn can generate self-standing films.
December 25, 2007, 14:40, FENS L062