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Advances In Dip-Pen Nanolithography For Applications In Engineering Biosensors And Biomaterials

Robert Marchmont Ph.D

Nanoink Inc, 8025 Lamon Ave, Skokie, IL 60077 USA, E-mail

Dip Pen Nanolithography® (DPN®) is an established method of nanofabrication in which materials are deposited onto a surface via a sharp tip.[1] DPN enables controlled deposition of a variety of materials with nanoscale registry onto a diverse range of substrates and existing structures (such as electronic chips and optical surfaces). Recent advances in DPN technology has resulted in the ability to directly print biologically relevant materials, including proteins and DNA, on to a variety of surfaces under ambient conditions. This has great potential for utilization in the fields of cell biology and biosensors. The deposition of biomaterials at sub-cellular scales in complex multiplexed patterns holds huge promise for studies in life sciences. Until now the technology available to create these patterns has been overly complex, unacceptably slow, and unreliable.


This open presentation will cover applications that utilise ‘molecular’ and ‘liquid’ inks for applications in nanoengineering. For example, sub-cellular scale patterns of hydrogel materials with defined mechanical properties could be utilized as scaffolds for tissue engineering and for in vitro cell culture studies. Other liquid inks include lipids and functional polymers with electrical, chemical or optical properties. Molecular inks, such as alkane thiols, allow the rapid fabrication of very small features (~15 nm) with nanoscale registry. These patterns can be used as etch resists and templates for the assembly of subsequent materials. All of the techniques presented and are easily scalable over cm2 areas using recent advances in MEMS technology.

Event Address


25 Temmuz 2011