seminar: Dr. Erinç Şahin, June 04 2010, Friday, FENS L063, 13:40,P.M.

Utilization of peptides/proteins in synthesis of nanomaterials                  

 Dr. Erinç Şahin (University of Delaware)

Abstract:


a)    Self-assembling structures in nanomaterials design and protein-polymer hybrids as self-assembling nanostructures


b)    Expression of de novo designed proteins for synthesis of nanomaterials:


Discovery of an evolutionary pattern on amino acid choices of organisms


Synthesis of nanomaterials is dominated by two schools of design:
top-down and bottom-up approaches. Followed by a discussion of examples
from both schools of design, I will be presenting a case of bottom-up
approach, using self-assembly potential of peptide-PEG copolymers that
carry desirable characteristics from each component. In addition, I
will be discussing challenges of production of de novo designed
recombinant proteins from an evolutionary perspective, suggesting some
insights on selective pressures on isoelectric points of proteins.


Sahin, E., Kiick, K. “Macromolecule-induced assembly of coiled-coils in
alternating multiblock polymers”, Biomacromolecules, 2009, 10 (10), pp
2740-2749

June 04 2010, Friday, FENS L063, 13:40-15:00 P.M.