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Academic Seminar (Course) FENS G032 SEMINAR:Asymptotically optimal energy consumption and inventory...

We study a make-to-stock manufacturing system in which a single server makes the production. The server consumes energy, and its power consumption depends on the server state: a busy server consumes more power than an idle server, and an idle server consumes more power than a turned-off server. When a server is turned on, it completes a costly set-up process that lasts a while. We jointly control the finished goods inventory and the servers energy consumption. The objective is to minimize the long-run average inventory holding, backorder, and energy consumption costs by deciding when to produce, when to idle or turn off the server, and when to turn on a turned-off server. Because the exact analysis of the problem is challenging, we consider the asymptotic regime in which the server is in the conventional heavy-traffic regime. We formulate a Brownian control problem (BCP) with impulse and singular controls. In the BCP, the impulse control appears due to server shutdowns, and the singular control appears due to server idling. Depending on the system parameters, the optimal BCP solution is either a control-band or barrier policy. We propose a simple heuristic control policy from the optimal BCP solution that can easily be implemented in the original (non-asymptotic) system. Furthermore, we prove the asymptotic optimality of the proposed control policy in a Markovian setting. Finally, we show that our proposed policy performs close to optimal in numerical experiments.

13.11.2024 - All Day
Academic Seminar (Course) Online SEMINAR:Computational Bionanodesign & Molecular Electronics..

The realization of nanoscale devices largely depends on our ability to control and manipulate both the molecular interactions and charge transport within and among molecules. The field of molecular electronics uses molecules as electronic components and has intriguing applications in a variety of fields, including storage devices, logic circuits, optoelectronics, and biosensors. Molecular electronics offer various fundamental advantages. First, the size of molecules used is in the realm of nanometers, and thus the device packing densities can be increased with lower cost, high efficiency, and low power dissipation. Second, one can use specific intermolecular interactions to form desired geometries via self-assembly in a bottom-up fashion. Therefore, various organic and inorganic molecules have been the subject of extensive research to engineer novel electronic components. For more than two decades, DNA/RNA has been at the forefront of molecular electronics research. Facilitated by the advance of synthetic biology, designer DNA with predetermined sequences can be readily synthesized for various applications (e.g., biosensors, single molecule transistors, DNA origami, DNA nanopores and DNA storage) in the emerging field of molecular electronics. However, the lack of control of charge transport significantly limits its application in nanoelectronics. In this talk, we describe how novel peptides and/or oligonucleotides can be designed with specific charge transport properties using novel computational/engineering approaches and give examples of their potential utilizations in technology and medicine.

06.11.2024 - All Day
Academic Seminar (Course) FENS G035 SEMINAR:Engineering Micro/Nano Resonators for Environmental...

The design of sensor systems capable of functioning in ambient air or liquid media is highly sought after for label-free sensing in environmental and biological problems. Within this vision, I will outline various sensor platforms we have developed with micro/nanoscale resonators, using nano-electromechanical systems (NEMS) and microwave technologies. Nanomechanical resonators can achieve mass resolution on the order of several MegaDaltons (MDa) under ambient conditions, enabling the characterization of single nanoparticles and viruses that are in the hundred-MDa mass range. However, transporting analytes to the nanoscale sensing region had remained a significant hurdle. With the integration of an ion lens on the NEMS chip 1, we demonstrated high-efficiency nanoparticle detection using the self-focusing NEMS technology. We recently improved this technique with the use of devices featuring a central paddle-like collection area, which yields higher efficiency and requires simpler electronics 2. While NEMS devices are sensitive to inertial mass changes, microwave resonators can probe the same analytes through their electrical polarizability. For detection of cells and nanoparticles in liquid, we have developed microwave sensors with micro/nanoscale sensing regions. I will give an overview of recent experiments, such as classifying materials based on permittivity at the microscale 3, detecting nanoparticles using a microwave nanopore 4, and more recently conducting drug-resistance tests on cancer cells. I will conclude by discussing potential trends for novel sensing scenarios, such as multi-physical sensing.

06.11.2024 - All Day
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