| Faculty of Engineering and Natural Sciences

Nur Mustafaoğlu Faculty of Engineering and Natural Sciences Faculty Member (216) 483 9962 nurmustafaoglusabanciunivedu

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Faculty Member

Areas of Interest

Bioengineering, organ-on-a-chip models, blood-brain barrier, brain diseases, stem cell technologies, drug delivery, nanoparticles, liposomes, biosensors, disease detection, neurobiology

Memberships

2023 – Present Member, The European Association for Cancer Research (EACR) 2023 – Present Member, Turkish Biochemical Society (TBD) 2022 – Present Member, Nanomedicine European Technology Platform (ETPN) 2019 – 2021 Member, American Association of Pharmaceutical Scientists (AAPS) 2018 – 2021 Member, International Brain Barriers Society (IBBS) 2016 – 2018 Student Member, American Chemical Society (ACS) 2015 – 2019 Member, American Institute of Chemical Engineers (AIChE) 2014 – 2017 Student Member, The Antibody Society

Çakır, Nilüfer and Oncel, Hatice and Ozkan, Aylin and Bicak, Dilan and Akgun Bas, Sibel and Mustafaoğlu, Nur (2025) "Developing immunoniosomes (INs): antibody and fab conjugations of niosomal nanoparticles via UV-NBS and EDC/NHS chemistry for treating glioblastoma cells", International Journal of Pharmaceutics: X, Vol.10 (SCI)

Çakır, Nilüfer and Altas, Burcu Okmen and Kalaycioglu, Gokce Dicle and Mustafaoğlu, Nur and Aydogan, Nihal (2025) "Development and characterization of DHA-integrated nanostructured lipid carrier formulations for enhanced cellular binding and uptake", Colloids and Surfaces A: Physicochemical and Engineering Aspects, Vol.720 (SCI)

Sevimli, Gülşah and Kuş, Eda and Baran, Gülin and Marashian, Mahya and Tabatabaei, Nasrollah and Mustafaoğlu, Nur (2025) "Graphene nanoplatelets enhance neuronal differentiation of human bone marrow mesenchymal stem cells", Biological Research, Vol.58, No.1 (SCI)

Soliman Tolba, Yomna Soliman Mohammed and Al-Khodor, Jana and Yildirim Köken, Gülnaz and Mustafaoğlu, Nur (2025) "A guide for blood-brain barrier models", FEBS Letters, Vol.599, No.5, 599-644 (SCI)

Çakır, Nilüfer and Öztürk, Naile and Kara, Aslı and Zarrabi, Ali and Mustafaoğlu, Nur (2024) "Optimizing niosomal formulations for enhanced cellular applications: a comparative case study with l-α-lecithin liposomes", Advances in Pharmacological and Pharmaceutical Sciences, Vol.2024, No.1 (ESCI)

Rahmani Dabbagh, Sajjad and Rezapour Sarabi, Misagh and Birtek, Mehmet Tugrul and Mustafaoğlu, Nur and Zhang, Yu Shrike and Tasoglu, Savas (2023) "3D bioprinted organ-on-chips", Aggregate, Vol.4, No.1 (ESCI)

Dabbagh, Sajjad Rahmani and Ozdalgic, Berin and Mustafaoğlu, Nur and Tasoglu, Savas (2022) "Three-dimensional-bioprinted liver chips and challenges", Applied Sciences (Switzerland), Vol.12, No.10 (SCI)

Tajeddin, Alireza and Mustafaoğlu, Nur (2021) "Design and fabrication of organ-on-chips: promises and challenges", Micromachines, Vol.12, No.12 (SCI)

1. Danny D. Sahtoe, Adrian Coscia*, Nur Mustafaoglu*, Lauren M. Miller*, Daniel Olal, Ivan Vulovic, Ta-Yi Yu, Inna Goreshnik, Yu-Ru Lin, Lars Clark, Florian Busch, Lance Stewart, Vicki H. Wysocki, Donald E. Ingber, Jonathan Abraham, and David Baker (2021), Transferrin receptor targeting by de novo sheet extension, Proceedings of the National Academy of Sciences of the United States of America, 118 (17), e2021569118. *Contributed equally

https://www.pnas.org/content/118/17/e2021569118.short

2. Tae-Eun Park*, Nur Mustafaoglu*, Anna Herland, Ryan Hasselkus, Robert Mannix, Edward A. FitzGerald, Rachelle Prantil-Baun, Alexander Watters, Olivier Henry, Maximilian Benz, Henry Sanchez, Heather McCrea, Liliana Christova Goumnerova, Hannah W. Song, Sean P. Palecek, Eric Shusta, and Donald E. Ingber (2019), Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies, Nature Communication, 10(1), 2621. *Contributed equally https://doi.org/10.1038/s41467-019-10588-0.

3. Golnaz Morad, Christopher V. Carman, Elliott J. Hagedorn, Julie R. Perlin, Leonard I. Zon, Nur Mustafaoglu, Tae-Eun Park, Donald E. Ingber, Cassandra C. Daisy, and Marsha A. Moses (2019), Tumor-derived extracellular vesicles breach the intact blood brain barrier via transcytosis, ACS Nano, 13(12), 13853-13865. https://doi.org/10.1021/acsnano.9b04397.

4. Jared F. Stefanick, David T. Omstead, Jonathan D. Ashley, Peter E. Deak, Nur Mustafaoglu, Tanyel Kiziltepe, Basar Bilgicer (2019), Optimizing design parameters of a peptide targeted liposomal nanoparticle in an in vivo multiple myeloma disease model after initial evaluation in vitro. Journal of Control Release, 311, 190-200. https://doi.org/10.1016/j.jconrel.2019.08.033.

5. Nur Mustafaoglu, Tanyel Kiziltepe, Basar Bilgicer (2017). Site-specific conjugation of antibody on gold nanoparticle surface for one-step diagnosis of prostate specific antigen with dynamic light scattering, Nanoscale, 9, 8684-8694. https://doi.org/10.1039/C7NR03096G.

6. Nur Mustafaoglu, Tanyel Kiziltepe, Basar Bilgicer (2016). Antibody purification via affinity membrane chromatography method utilizing nucleotide binding site targeting with a small molecule, Analyst, 141, 6571-6582. https://doi.org/10.1039/C6AN02145J.

7. Nur Mustafaoglu, Nathan J. Alves, Basar Bilgicer (2015). Oriented immobilization of Fab fragments by site-specific biotinylation at the conserved nucleotide binding site for enhanced antigen detection, Langmuir, 31, 9728-9736. https://doi.org/10.1021/acs.langmuir.5b01734.

8. Nur Mustafaoglu, Nathan J. Alves, Basar Bilgicer (2015). Site-specific fab fragment biotinylation at the conserved nucleotide binding site for enhanced Ebola detection. Biotechnology and Bioengineering, 112, 1327-1334. https://doi.org/10.1002/bit.25558.

9. Nathan J. Alves, Nur Mustafaoglu, Basar Bilgicer (2014). Conjugation of a reactive thiol at the nucleotide binding site (NBS) for site-specific antibody functionalization, Bioconjugate Chemistry, 25, 1198-1202. https://doi.org/10.1021/bc500211d.

10. Nathan J. Alves, Nur Mustafaoglu, Basar Bilgicer (2013). Oriented antibody immobilization by site-specific UV photocrosslinking of biotin at the conserved nucleotide binding site for enhanced antigen detection, Biosensors and Bioelectronics, 49, 387–393. https://doi.org/10.1016/j.bios.2013.05.052.

11. Gokhan Bilir, Nur Mustafaoglu, Gonul Ozen, Baldassare Di Bartolo (2011). Characterization of emission properties of Er3+ ions in TeO2–CdF2–WO3 glasses. Spectrochimica Acta Part A: Molecular Spectroscopy, 83, 314-321. https://doi.org/10.1016/j.saa.2011.08.037.